RB JaMycal Hasty (ankle)
DL Maurice Hurst (calf)
RB Elijah Mitchell (rib, finger)
T Trent Williams (not injury related – resting player)
Mitchell had a procedure on his finger after fracturing it Monday night. The good news is head coach Kyle Shanahan sounds relatively optimistic about his chances to play Sunday in Jacksonville. Hurst could wind up missing a few more weeks with a bad calf injury, and Hasty missed Week 10 with that ankle issue. His absence to begin Week 11 isn’t a great sign for his availability.